Volume 14 No 1 (2022): International Journal of Early Childhood Special Education

Evaluate the Effect of Vitamin D Supplementation on Mortality and Intubation Rate in COVID-19 Patients: A Systematic Review and Meta-Analysis


Shima Sadat Aghahosseini, Arezou Sam Daliri, Zahra Siah Mansour Khorin, Elham Mohammadzadeh, Mehdi Vafadar

DOI: 10.9756/INT-JECSE/V14I1.367

Keywords: COVID-19, Vitamin D Supplementation, Mortality


Abstract

Background and aim: the purpose of present study was Evaluate the effect of vitamin D supplementation on mortality and intubation rate in COVID-19 patients Method:all articles published in international databases such as PubMed, Scopus, Science Direct, Embase between January 2019 and March 2022 included. 95% confidence interval on risk ratio (RR) were done with fixed effect model and Mantel-Haenszel method. Meta-analysis of data collected from selected studies was performed using STATA.V16 software. Result: full text of 31 articles was reviewed; finally, eight articles entered the analysis. Risk ratio of Effect on mortality and intubation rate between Vitamin D and standard-of-care regarding was -0.09 (RR; 95% CI (-0.28, 0.10), p=0.36) and -0.25 (RR; 95% CI (-0.59, 0.08), p=0.14). Conclusion: According to the meta-analysis, vitamin D administration is not effective on low intubation rate and reduce mortality rate of Covid-19 patients.

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Volume 14 No 1 (2022): International Journal of Early Childhood Special Education

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Research Articles

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