Introduction:Although regular blood transfusions and strict iron chelation therapy have increased the life expectancy of thalassemia patients in recent years, these patients nevertheless suffer various consequences, the most prevalent of which is cardiovascular. One of the life-threatening consequences of the chronic hypercoagulable state and thrombotic episodes that result from haemostatic attention in people with thalassemia, but they are more common in people with thalassemia intermedia. Thrombosis is a relatively uncommon condition. Thrombosis is a rare occurrence. We talk about a patient who had a splenectomy six years ago but did not keep up with her followup visits and ended up in our clinic with two months of steadily worsening exercise dyspnoea. In thalassaemia major [TM] patients, diabetes mellitus [DM] is a significant concern. Main Symptoms and Important Clinical Findings: A 31-year-old case of thalassemia major with type 1 diabetic reported to rural hospital. CBC (complete blood count) and peripheral blood smear (PBS), hypochromic cells confirmed thalassemia. The Main Diagnosis, Therapeutic Intervention, And Outcomes:A 31-year-old thalassemia major with type 1 diabetes who has come for treatment at a specialized centre that provides a comprehensive case for people with betathalassemia, including preparing treatment programmes. Treatment in such a centre ensured that a competent health care team would assess each client and family member. All procedures were completed as requested. Conclusion:This study looked at improving public health and hospital-based health promotion programme. In TM patients, IFG and DM risk factors, as well as the volume of blood transfusions per occasion and splenectomy, are all aspects to consider

Endocrinology, thalassemia, consequences, anemia, Blood.