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Research Article | Open Access
Volume 14 2022 | .
CORRELATION OF THE C-REACTIVE PROTEIN WITH RENAL MARKERS, SPO2 ANDLACTATE DEHYDROGENASE IN MECONIUM ASPIRATE PATIENTS
Dhiraj Mahaseth, Savita Rathore, M Anil Kumar, Ashok Kumar Jha,Ashish Kumar Sharma, Mohd Ajmal, Bijay Kumar Mahaseth, Ranjan Kumar Dixit
Pages: 556-559
Abstract
Meconium is the earliest stool of a newborn.[1].Meconium is a shady olive color, sticky fluid that’s amassed in the fetal intestinal tract at some stage in the 3rd trimester of pregnancy, being the initial intestinal expulsion out within 48 hours after birth. Antenatal or intrapartum meconium discharge is called as meconium staining of amniotic fluid (MSAF)and it has been estimated to occur in 8- 20% [2]. Meconium aspiration syndrome (MAS) is the neonatal respiratory distress caused by the appearance of meconium in the tracheobronchial airways [3].When aspirated, meconium can cause obstacle, gas ambushing, exasperation and inflammation leading to damaged lung surfactant, pneumonitis and hypoxia and influence the reactivity of both vascular and airway smooth muscle. It can also create a medium for bacteria to grow in the lung [4, 5]. Its seems that the hypoxia leads to lactate formation from pyruvate in MAS patients. Newborns with meconium aspiration syndrome often have inappropriate secretion of antidiruetic hormones.
Keywords
Meconium aspiration syndrome, CRP, LDH, Inflammation
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