Research Article | Open Access
PHYTOCHEMICALANALYSIS,ANTIOXIDANTANDANTIDIABETIC
Sangiya K, C.Naveen Kumar
Pages: None-None
Abstract
The edible seaweed, Sargassum wightii, was investigated for its antidiabetic potential through in vitro enzyme inhibitory
assays. Among the various extracts, extracts of petroleum ether and Syl ethyl acetate. wightii showed significant
inhibitory effects against α-amylase. Methanol extract for S. wightii showed very high inhibition against dipeptidyl
peptidase and moderate antioxidant activity was observed in the release of acetone S. wightii. Similarly, the hexyen
extract of S. polycystum showed very high inhibition against α-amylase and S-extract methanol. polycystum inhibition
significantly against α-glucosidase as well. The antioxidant activity was negative. Exit was investigated with in vitro
cytotoxicity, DNA fragmentation in macrophages and hemolytic activity against erythrocytes, but no significant toxicity
was detected by any of the extracts. Gas chromatography – mass spectrometry reveals the presence of antidiabetic
compound fucosterol and other major bioactive compounds, providing insight into the antidiabetic and antioxidant
properties of this compound. This study revealed possible mechanisms of antidiabetic in vitro action, and these two
marine plants may have antidiabetic action in vivo. Seaweed, that is, the great seaweed, comprises a group of
photosynthetic plants, which it is believed that evolution did not extend to the earth's vegetation. in general, the
morphology of algae is much simpler than that of plant plants. There is a limited variety of functional cells and, indeed,
many known unicellular algae are scientifically related to marine plants. To date as algae metabolism has been studied, it
appears to be similar in many ways to earthy plants, although the final metabolic product may be different.
Keywords
Sargassumwightii,phenol,flavonoid,carbohydrate,pigmentcontent, -Amylase.