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Research Article | Open Access
Volume 14 2022 | None
PRELIMINARY PHYTOCHEMICAL ANALYSIS AND ANTI GOUT ACTIVITY OF AQUEOUS EXTRACTS OF SELECTED MEDICINAL PLANTS . ( NEEM AND TULSI )
Srivarsha Ranjeet, V. Vishnu Priya, Gayathri.R, Kavitha.S
Pages: 42-48
Abstract
Introduction: GOUT is a form of arthritis characterised by severe pain, redness, tenderness in joints. In gout,elevation of uric acid in the blood triggers the formation of crystals, causing joint pain. India is a country that isrich in medicinal plants. Therefore its flora might offer promising therapies for gout. Neem and Tulsi exhibitxanthine oxidase inhibitory activity. Neem and Tulsi have natural bioactive compounds which includeflavonoids, proteins, amino acids, terpenoids, alkaloids, carbohydrates, saponins, steroids. Aim : Aim of this study is to estimate the anti gout activity of aqueous extract of selected medicinal plants withstandard drug (allopurinol). Materials and methods : Phytochemical screening and anti gout activity of Neem and Tulsi were analysed andcomparison with standard drug (allopurinol) is also done . Results : NEEM and TULSI extract shows an increase in xanthine oxidase inhibition in tested concentration.Phytochemical analysis showed that neem contains proteins, amino acids, flavonoids, alkaloids, carbohydrates,saponins and tulsi contains terpenoids, flavonoids , alkaloids, carbohydrates, steroids. Conclusion: From this study it is concluded that medicinal plants like Neem and Tulsi exhibit anti goutactivity.The standard drug allopurinol showed greater percentage of inhibition of xanthine oxidase enzyme thanthat of tulsi , neem extracts in all given tested concentrations.
Keywords
Preliminary phytochemical analysis , Antigout activity , Innovative technique, Aqueous extract,Neem, Tulsi, novel method
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