Viral hepatitis is a major human health problem worldwide. Hepatitis B is a viral disease with a high incidence and prevalence worldwide and it can cause acute and chronic liver disease. Approximately (8%) of the world's population has been infected with HBV, and more than 300 million people throughout the world are affected by hepatitis B virus (HBV). Around 4% of people have been affected of HBV in India. Serological test is an important tool for the identification of the HBV. Infection with HBV is associated with characteristic changes in the serum levels of hepatitis B antigens and antibodies. This is a case-control studywith viral disease in State of Puducherry, the study population consists of 125 cases and 102 HBV patients and 23 controls residing in the same region. Data were collected through standard questionnaire and the results were compiled and interpreted. The results of this study indicate that sera from patients with alcoholic a chronic disease interfering with the normal functioning of the liver; the major cause is chronic alcoholism. The present investigation aims to assess the status of Hepatitis B virus patients and control in and around Puducherry and the results have been discussed.

Epidemiology; viral hepatitis; Chronic Hepatitis-B Virus.