Anticoagulants are medicines that help prevent blood clots. They're given to people at a high risk of getting clots, to reduce their chances of developing serious conditions such as strokes and heart attacks. Warfarin, which acts by antagonizing the effect of vitamin K, is one of the most commonly used oral anticoagulants. Its effect is measured by international normalized ratio (INR), which is a measure of a patient's prothrombin time divided by the laboratory control value of prothrombin time.Continuous oral anticoagulant therapy has been used to decrease the risk of thromboembolism for more than half a century, prolonging the lives of thousands of patients. Heparin is used in anticoagulation bridge therapy, as it has a faster onset and offset action compared with warfarin. Stopping warfarin can increase the risk of cerebrovascular accidents (CVA).

Anticoagulants, Bleeding, Blood clot, Heparin, Warfarin, Innovative study