Cholinesterase isa family of enzymes thatcatalyze thehydrolysisoftheneurotransmitteracetylcholineintocholineandaceticacid.Thereare2types;Acetylcholinesterase also known as erythrocyte cholinesterase found in RBCs cell membrane andpseudocholinesteraseknownasplasmacholinesterasewhichissynthesizedmainlyinhepatocyte and is released into blood and its activity is reduced in liver dysfunction due toreduced synthesis.Cholinesterase represents a group of enzymes that hydrolyze acetylcholineandothercholineesters.Therearetwomaintypesofcholinesterasewithdifferentbiochemical properties: true or specific cholinesterase or acetylcholinesterase found in allexcitabletissues(centralandperipheralnervoussystemandmuscles)andinerythrocytes.Itisahighturnoverenzymewithhighaffinityforacetylcholine,inhibitedathighconcentrationsofacetylcholine,andwith lowaffinity fornonchlorineesters

Cholinesterase,LiverDiseases