The aim of the study was to study the results of ultrasound dopplerography of the vessels of the head and heart in patients with the neuroischemic form of diabetic foot syndrome associated with chronic heart failure in ischemic heart disease. Material and methods of research. During 2021, on the basis of the Department of Surgery of AndGovMI and RSNPMCE of the Ministry of Health of the Republic of Uzbekistan, the estate of Academician E.H. Turakulov, 64 patients with SDS neuroischemic form were examined. The patients were divided into 4 groups: 1 gy – patients with type 2 diabetes and neuroischemic form of SDS and CHD – 15 patients , Group 2 – patients with type 2 diabetes and neuroischemic form of SDS without CHD – 18 patients, group 3 – patients with type 2 diabetes and neuroischemic form of SDS, CHD and dyscirculatory encephalopathy 2-3 ct – 16 patients. Group 4 – persons with coronary heart disease without disorders of carbohydrate metabolism – 15 patients. Healthy volunteers (n=20) formed a control group. All patients were subjected to general clinical, biochemical hormonal and instrumental methods of examination - ultrasound Dopplerography of the vessels of the brain, lower extremities, ECG, Echo ECG, bacteriological analysis of the discharge from the wound, as well as statistical methods. The results of the study. In the main 3 groups of patients with type 2 diabetes, during metabolic stimulation of the endothelium of SMA, a negative response was obtained in 38 out of 45 patients (84.4%) of the patient, in 7 (15.5%) patients – a paradoxical SMA response. In group 4 (comparison group), when assessing cerebrovascular reactivity, reliable dynamics of the peak systolic blood flow rate of SMA up to 14%, the time-averaged maximum blood flow rate up to 28% (p<0.05) was obtained. Only 6 (40%) patients had a negative SMA reaction. There is a significant difference in the indicators of central hemodynamics in the studied groups compared with the norm: for example, LV CDR, CSR, CDR, LV CSR (p<0.05), data on the average pressure in the pulmonary artery, the time of slowing down the blood flow of early diastolic filling, TSSLJ (p<0.001), PV, the ratio of peak wave velocities E and A, the time of isovolumic relaxation of LV, MMLJ, IMLJ (p <0.05). Conclusions. 1. The combined effect of hemodynamic and metabolic disorders has the greatest damaging effect on the endothelium of the arteries. In all patients with type 2 diabetes mellitus in combination with coronary heart disease, dysfunction of the endothelial mechanism of vascular tone regulation was revealed - in 84%. 2. Among the risk factors, hereditary burden of diabetes prevailed - only 21 cases out of 60 (35%), smoking – only 49 cases (81.6%), alcoholism – 16 cases (26.6%). 3. Significant deviations of central hemodynamic parameters were revealed in the studied groups.

diabetic foot syndrome, dopplerography