The bad effects of high blood sugar cause some parts of the body that have nothing to do with the immune system may also make them more likely to get sick. Poor local circulation, which can be caused by both macrovascular disease and microvascular dysfunction, can make it take longer to respond to infections and for wounds to heal [1]. When a person has sensory neuropathy in their legs, they may not feel it when they are hurt. This can cause them to not take care of small wounds properly, which can make them more likely to get an infection [2]. Autonomic neuropathy can cause the bladder to not empty all the way, which can make it easier for bacteria to take hold of the urinary tract [3]. Also, there is evidence that a high amount of glucose in the urine can make some bacteria and yeasts grow faster [4]. People with diabetes have been known to get infections in their bladder, kidneys, vagina, gums, feet, and skin [5].

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